10–14 Nov 2025
Office of Grants and Research
Africa/Accra timezone

Declining Incidence, Rising Fatality: A Surveillance-Based Temporal Analysis of Severe Malaria Admissions in Ashanti Region, Ghana, 2018 to 2022.

Not scheduled
45m
Office of Grants and Research

Office of Grants and Research

Poster Presentation

Speaker

Courage Eli Yevugah (Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legion - Accra, Ghana.)

Description

Background: Severe malaria remains a threat in sub-Saharan Africa, contributing to morbidity and mortality despite control efforts. In Ghana’s Ashanti region, it overwhelms healthcare during seasonal peaks.
Objectives: Examine severe malaria admissions and deaths in health facilities from 2018 to 2022 to identify trends in the Ashanti region.
Methods: We analyzed over 55,000 admission records from Ghana’s District Health Information System (DHIMS 2). Monthly incidence per 10,000 admissions and case fatality rates (CFRs) were calculated, using cumulative summation (CUSUM-2) thresholds to highlight anomalies. A linear trendline showed direction, and Kendall’s Tau tested monotonic trend significance at 5% alpha.
Results: Incidence oscillated between 548.2 and 87.9, with rainy season peaks and dry season troughs, showing a significant decline (τ = -0.2, p = 0.017). CFRs rose from 0.2% in January 2018 to 1.0% in November 2021, with a significant increase (τ = 0.2, p = 0.035). Threshold analysis revealed aberrations in July–August 2020 and July–September 2021, coinciding with COVID-19 measures and seasonal patterns.
Conclusion: The decline in admissions suggests progress in control, but rising CFRs highlight gaps in care quality and timeliness. Seasonal peaks and COVID-19-related aberrations underscore the need for adaptive surveillance. These findings emphasize sustaining prevention while strengthening clinical care and emergency readiness during high-risk periods.
Keywords: Severe malaria, Incidence, Deaths, Surveillance, DHIMS 2, Ghana.

Primary authors

Courage Eli Yevugah (Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legion - Accra, Ghana.) Dr Harriet Afran Bonful (Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legion - Accra, Ghana.)

Co-authors

Dr Bismark Sarfo (Department of Epidemiology and Disease Control, School of Public Health, University of Ghana, Legion - Accra, Ghana.) Mr Michael Opoku Mireku (Atebubu-Amanten Municipal Health Directorate, Ghana Health Service)

Presentation materials

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