10–14 Nov 2025
Office of Grants and Research
Africa/Accra timezone

Machine learning-based risk prediction models for maternal and newborn adverse pregnancy outcomes in low- and middle-income countries: a scoping review

13 Nov 2025, 14:00
15m
Office of Grants and Research

Office of Grants and Research

Oral Presentation Health Systems, Basic sciences, Biomedical Advances, pharmaceutical Sciences and Human Wellbeing

Speakers

Mr Douglas Aninng Opoku (School of Public Health, Kwame Nkrumah University of Science and Technology)Mr Eliezer Odei-Lartey (Kintampo Health Research Centre)

Description

Background: Adverse pregnancy outcomes (APOs) remain a major public health issue, especially in low- and middle-income countries (LMICs). Machine learning (ML)-based risk prediction models present opportunities for early identification and intervention, yet there is limited evidence of their application and predictive performance in LMICs. The review aimed to map the existing evidence on ML models and input features used to predict APOs in LMICs.
Methods: This review was guided by the Joanna Briggs Institute methodology for scoping reviews and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analysis extension for Scoping Reviews. A comprehensive literature search was conducted in PubMed, Cochrane Library, Web of Science and Scopus for articles from January 1, 2000, to June 26, 2024.
Results: Our search strategy yielded 4,680 records from which 351 duplicates were removed. After titles and abstracts screening, 114 full-text articles were assessed for full-text screening, out of which 25 were selected for inclusion in the review. An additional nine articles were identified from the references of the included studies, resulting in 34 being included in the final review. All the ML models used across the studies were supervised learning. The features most commonly used to train the ML models comprised maternal characteristics, clinical and obstetric history.
Conclusion: This review highlights the evolving yet limited application of ML-based risk prediction models for APOs in LMICs. Validating these models across different populations may be crucial for their integration into routine clinical care, ultimately enhancing maternal and child health.

Primary authors

Mr Eliezer Odei-Lartey (Kintampo Health Research Centre) Mr Francis Appiah (School of Public Health, Kwame Nkrumah University of Science and Technology) Dr George Adjei (University of Cape Coast, Cape Coast, Ghana) Mr Jonathan Gmanyanmi (School of Public Health, Kwame Nkrumah University of Science and Technology) Dr Joseph Osarfo (University of Health and Allied Sciences, Ho, Ghana) Prof. Peter Agyei-Baffour (School of Public Health, Kwame Nkrumah University of Science and Technology) Ms Sandra Lartey (University Hospital, Kwame Nkrumah University of Science and Technology) Mrs Stephaney Gyaase (Kintampo Health Research Centre) Prof. Yeetey Enuameh (School of Public Health, Kwame Nkrumah University of Science and Technology)

Co-author

Mr Douglas Aninng Opoku (School of Public Health, Kwame Nkrumah University of Science and Technology)

Presentation materials